Influence of exposure time on gene expression by human intestinal epithelial cells exposed to Lactobacillus acidophilus.
نویسندگان
چکیده
Analysis of global temporal gene expression by human intestinal cells when exposed to Lactobacillus acidophilus revealed induction of immune-related pathways and NF-κB target genes after a 1-h exposure, compared to a 4- or 8-h exposure. Additionally, an L. acidophilus derivative expressing covalently bound flagellin resulted in increased induction of il8, cxc1, and cxcl2 compared to the parent L. acidophilus.
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ورودعنوان ژورنال:
- Applied and environmental microbiology
دوره 78 14 شماره
صفحات -
تاریخ انتشار 2012